Reprogramming of fatty acid metabolism in cancer

A common feature of cancer cells is their ability to rewire their metabolism to sustain the production of ATP and macromolecules needed for cell growth, division and survival. In particular, the importance of altered fatty acid metabolism in cancer has received renewed interest as, aside their princ...

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Vydané v:	British journal of cancer Ročník 122; číslo 1; s. 4 - 22
Hlavní autori:	Koundouros, Nikos, Poulogiannis, George
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London Nature Publishing Group UK 01.01.2020 Nature Publishing Group
Predmet:	1-Phosphatidylinositol 3-kinase 631/67/2327 631/80/86/2365 AKT protein Biomedical and Life Sciences Biomedicine Cancer Cancer Research Carcinogenesis - drug effects Carcinogenesis - metabolism Cell survival Drug Resistance Epidemiology Epigenome Fatty acids Fatty Acids - metabolism Humans Lipogenesis - drug effects Macromolecules Metabolism Metastases Molecular Medicine Neoplasms - drug therapy Neoplasms - metabolism Oncology Oxidation Phosphatidylinositol 3-Kinases - metabolism Phosphoinositide-3 Kinase Inhibitors - therapeutic use Proto-Oncogene Proteins c-akt - antagonists & inhibitors Proto-Oncogene Proteins c-akt - metabolism Review Review Article Signal transduction Signal Transduction - drug effects TOR protein TOR Serine-Threonine Kinases - antagonists & inhibitors TOR Serine-Threonine Kinases - metabolism Tumor microenvironment Tumor Microenvironment - drug effects Tumors
ISSN:	0007-0920, 1532-1827, 1532-1827
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