KRAS mutation in pancreatic cancer

Pancreatic cancer is a recalcitrant cancer with one of the lowest 5-year survival rates. A hallmark of pancreatic cancer is the prevalence of oncogenic mutation in the KRAS gene. The KRAS oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network...

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Bibliographic Details

Published in:	Seminars in oncology Vol. 48; no. 1; p. 10
Main Author:	Luo, Ji
Format:	Journal Article
Language:	English
Published:	United States 01.02.2021
Subjects:	Humans Mutation Pancreatic Neoplasms - drug therapy Pancreatic Neoplasms - genetics Proto-Oncogene Proteins p21(ras) - genetics Signal Transduction - genetics MAPK pathway G12C KRAS Targeted therapy Pancreatic cancer
ISSN:	1532-8708, 1532-8708
Online Access:	Get more information
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