Free water elimination improves test–retest reproducibility of diffusion tensor imaging indices in the brain: A longitudinal multisite study of healthy elderly subjects

Free water elimination (FWE) in brain diffusion MRI has been shown to improve tissue specificity in human white matter characterization both in health and in disease. Relative to the classical diffusion tensor imaging (DTI) model, FWE is also expected to increase sensitivity to microstructural chang...

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Bibliographic Details
Published in:	Human brain mapping Vol. 38; no. 1; pp. 12 - 26
Main Authors:	Albi, Angela, Pasternak, Ofer, Minati, Ludovico, Marizzoni, Moira, Bartrés‐Faz, David, Bargalló, Núria, Bosch, Beatriz, Rossini, Paolo Maria, Marra, Camillo, Müller, Bernhard, Fiedler, Ute, Wiltfang, Jens, Roccatagliata, Luca, Picco, Agnese, Nobili, Flavio Mariano, Blin, Oliver, Sein, Julien, Ranjeva, Jean‐Philippe, Didic, Mira, Bombois, Stephanie, Lopes, Renaud, Bordet, Régis, Gros‐Dagnac, Hélène, Payoux, Pierre, Zoccatelli, Giada, Alessandrini, Franco, Beltramello, Alberto, Ferretti, Antonio, Caulo, Massimo, Aiello, Marco, Cavaliere, Carlo, Soricelli, Andrea, Parnetti, Lucilla, Tarducci, Roberto, Floridi, Piero, Tsolaki, Magda, Constantinidis, Manos, Drevelegas, Antonios, Frisoni, Giovanni, Jovicich, Jorge
Format:	Journal Article
Language:	English
Published:	United States John Wiley & Sons, Inc 01.01.2017 Wiley John Wiley and Sons Inc
Subjects:	Aged Aged, 80 and over Aging Anisotropy Bioengineering Brain - diagnostic imaging Computer Science Diffusion Tensor Imaging Female Healthy Volunteers Humans Imaging Imaging, Three-Dimensional Life Sciences Longitudinal Studies Male Medical Imaging Middle Aged Reproducibility of Results Water - metabolism White Matter - diagnostic imaging free-water imaging brain diffusion tensor imaging longitudinal healthy elderly multisite diffusion MRI test-retest reproducibility MRI substantia-nigra reliability Schizophrenia snc parkinsons-disease tracking cerebral white-matter spatial statistics false discovery rate alzheimers-disease
ISSN:	1065-9471, 1097-0193
Online Access:	Get full text
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