Functional imaging of mitochondria in retinal diseases using flavoprotein fluorescence

Mitochondria are critical for cellular energy production and homeostasis. Oxidative stress and associated mitochondrial dysfunction are integral components of the pathophysiology of retinal diseases, including diabetic retinopathy (DR), age-related macular degeneration, and glaucoma. Within mitochon...

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Veröffentlicht in:	Eye (London) Jg. 35; H. 1; S. 74 - 92
Hauptverfasser:	Chen, Andrew X, Conti, Thais F, Hom, Grant L, Greenlee, Tyler E, Raimondi, Raffaele, Briskin, Isaac N, Rich, Collin A, Kampani, Reecha, Engel, Robert, Sharma, Sumit, Talcott, Katherine E, Singh, Rishi P
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Nature Publishing Group 01.01.2021
Schlagworte:	Acuity Diabetes Diabetes mellitus Diabetic retinopathy Diabetic Retinopathy - metabolism Eye Flavoproteins Flavoproteins - metabolism Fluorescence Glaucoma Glutathione Homeostasis Humans Macular degeneration Mitochondria Oxidative stress Retina Retina - diagnostic imaging Retina - metabolism Retinal Diseases - diagnostic imaging Retinal Diseases - metabolism Retinopathy Structure-function relationships
ISSN:	0950-222X, 1476-5454, 1476-5454
Online-Zugang:	Volltext
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