Highlighting attenuated total reflection Fourier transform infrared spectroscopy for rapid serum analysis

Recent studies have been more clinically relevant, and have shown ATR-FTIR coupled with multivariate analysis techniques to be effective and comparable in standards to current clinical detection and diagnosis methods, in the accurate detection of renal failure [10], ovarian and endometrial cancers [...

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Vydáno v:Trends in biotechnology (Regular ed.) Ročník 31; číslo 6; s. 327 - 328
Hlavní autoři: Dorling, Konrad M., Baker, Matthew J.
Médium: Journal Article
Jazyk:angličtina
Vydáno: England Elsevier Ltd 01.06.2013
Elsevier Limited
Témata:
Biomarkers
Biomarkers, Tumor - analysis
Biomedical research
Classification
Clinical
Clinical Laboratory Techniques - methods
Diagnosis
Endometrial cancer
Experiments
Fourier transforms
Histopathology
Humans
Infrared
Infrared spectroscopy
Internal Medicine
Medical diagnosis
Methods
Multivariate analysis
Neoplasms - diagnosis
Ovarian cancer
Rapid
Serum
Serum - chemistry
Spectroscopy, Fourier Transform Infrared - methods
Spectrum analysis
Clinical
Serum
Diagnosis
Infrared
Rapid
ISSN:0167-7799, 1879-3096, 1879-3096
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Popis
Shrnutí:Recent studies have been more clinically relevant, and have shown ATR-FTIR coupled with multivariate analysis techniques to be effective and comparable in standards to current clinical detection and diagnosis methods, in the accurate detection of renal failure [10], ovarian and endometrial cancers [11], and basal cell carcinoma [12] through the analysis of human blood serum. [...]there is a clear place for the use of ATR-FTIR instruments in the clinical setting, especially in the form of a serum screening and diagnostic tool for a plethora of diseases with further analysis of larger samples sets, ATR-FTIR has the potential to provide a rapid, dynamic, and responsive diagnostic environment based upon objective measures.
Bibliografie:ObjectType-Article-1
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ISSN:0167-7799
1879-3096
1879-3096
DOI:10.1016/j.tibtech.2013.03.010