Highlighting attenuated total reflection Fourier transform infrared spectroscopy for rapid serum analysis

Recent studies have been more clinically relevant, and have shown ATR-FTIR coupled with multivariate analysis techniques to be effective and comparable in standards to current clinical detection and diagnosis methods, in the accurate detection of renal failure [10], ovarian and endometrial cancers [...

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Bibliographic Details
Published in:Trends in biotechnology (Regular ed.) Vol. 31; no. 6; pp. 327 - 328
Main Authors: Dorling, Konrad M., Baker, Matthew J.
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01.06.2013
Elsevier Limited
Subjects:
Biomarkers
Biomarkers, Tumor - analysis
Biomedical research
Classification
Clinical
Clinical Laboratory Techniques - methods
Diagnosis
Endometrial cancer
Experiments
Fourier transforms
Histopathology
Humans
Infrared
Infrared spectroscopy
Internal Medicine
Medical diagnosis
Methods
Multivariate analysis
Neoplasms - diagnosis
Ovarian cancer
Rapid
Serum
Serum - chemistry
Spectroscopy, Fourier Transform Infrared - methods
Spectrum analysis
Clinical
Serum
Diagnosis
Infrared
Rapid
ISSN:0167-7799, 1879-3096, 1879-3096
Online Access:Get full text
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Summary:Recent studies have been more clinically relevant, and have shown ATR-FTIR coupled with multivariate analysis techniques to be effective and comparable in standards to current clinical detection and diagnosis methods, in the accurate detection of renal failure [10], ovarian and endometrial cancers [11], and basal cell carcinoma [12] through the analysis of human blood serum. [...]there is a clear place for the use of ATR-FTIR instruments in the clinical setting, especially in the form of a serum screening and diagnostic tool for a plethora of diseases with further analysis of larger samples sets, ATR-FTIR has the potential to provide a rapid, dynamic, and responsive diagnostic environment based upon objective measures.
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ISSN:0167-7799
1879-3096
1879-3096
DOI:10.1016/j.tibtech.2013.03.010