Natural killer cell immunotypes related to COVID-19 disease severity

Understanding innate immune responses in COVID-19 is important to decipher mechanisms of host responses and interpret disease pathogenesis. Natural killer (NK) cells are innate effector lymphocytes that respond to acute viral infections but might also contribute to immunopathology. Using 28-color fl...

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Veröffentlicht in:	Science immunology Jg. 5; H. 50
Hauptverfasser:	Maucourant, Christopher, Filipovic, Iva, Ponzetta, Andrea, Aleman, Soo, Cornillet, Martin, Hertwig, Laura, Strunz, Benedikt, Lentini, Antonio, Reinius, Björn, Brownlie, Demi, Cuapio, Angelica, Ask, Eivind Heggernes, Hull, Ryan M, Haroun-Izquierdo, Alvaro, Schaffer, Marie, Klingström, Jonas, Folkesson, Elin, Buggert, Marcus, Sandberg, Johan K, Eriksson, Lars I, Rooyackers, Olav, Ljunggren, Hans-Gustaf, Malmberg, Karl-Johan, Michaëlsson, Jakob, Marquardt, Nicole, Hammer, Quirin, Strålin, Kristoffer, Björkström, Niklas K
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 21.08.2020
Schlagworte:	Adaptive Immunity Betacoronavirus - genetics Betacoronavirus - immunology CD56 Antigen - metabolism Coronavirus Infections - blood Coronavirus Infections - epidemiology Coronavirus Infections - immunology Coronavirus Infections - pathology COVID-19 Female Flow Cytometry - methods Humans Killer Cells, Natural - immunology Lymphocyte Activation Male Middle Aged Pandemics Phenotype Pneumonia, Viral - blood Pneumonia, Viral - epidemiology Pneumonia, Viral - immunology Pneumonia, Viral - pathology Polymerase Chain Reaction Prospective Studies Protein Interaction Maps - immunology Receptors, KIR - metabolism SARS-CoV-2 Serologic Tests Severity of Illness Index Sweden - epidemiology Sweden
ISSN:	2470-9468, 2470-9468
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