DNA in extracellular vesicles: biological and clinical aspects

The presence of DNA in EVs, including exosomes and microvesicles, remains contentious as this field of study is still evolving. This review explores what is known about the biogenesis of EV‐DNA and the possible biological roles of DNA packaging into EVs. Moreover, we also discuss the potential clini...

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Veröffentlicht in:	Molecular oncology Jg. 15; H. 6; S. 1701 - 1714
Hauptverfasser:	Elzanowska, Julia, Semira, Christine, Costa‐Silva, Bruno
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States John Wiley & Sons, Inc 01.06.2021 John Wiley and Sons Inc Wiley
Schlagworte:	Adenocarcinoma AMP Apoptosis Biosynthesis Blood-brain barrier cancer Cell death cell‐free DNA Centrifugation Clinical aspects Cyclic GMP Deoxyribonucleic acid DNA DNA sequencing DNA viruses Epidermal growth factor Epidermal growth factor receptors EV‐DNA Extracellular vesicles Hepatitis B Human papillomavirus infection Interferon Lipids liquid biopsies Lung cancer Metastasis Micronuclei Mitochondrial DNA Non-small cell lung carcinoma Pancreas Plasma Polymerase chain reaction Prostate cancer Proteins Review Reviews Tumor cell lines cell-free DNA infection cancer extracellular vesicles EV-DNA liquid biopsies
ISSN:	1574-7891, 1878-0261, 1878-0261
Online-Zugang:	Volltext
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