An unexpected version of horror autotoxicus: anaphylactic shock to a self-peptide

EAE can refer either to experimental autoimmune encephalomyelitis or experimental allergic encephalomyelitis. Although EAE is classically a prototypic T helper 1 (T H 1) cell–mediated autoimmune disease, it can also be induced by T H 2 cells. Characteristically, the most severe manifestation of alle...

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Bibliographic Details
Published in:	Nature immunology Vol. 2; no. 3; pp. 216 - 222
Main Authors:	Pedotti, Rosetta, Mitchell, Dennis, Wedemeyer, Jochen, Karpuj, Marcela, Chabas, Dorothée, Hattab, Eyas M., Tsai, Mindy, Galli, Stephen J., Steinman, Lawrence
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01.03.2001 Nature Publishing Group
Subjects:	Allergens - immunology Allergies Anaphylaxis Anaphylaxis - etiology Anaphylaxis - immunology Anaphylaxis - pathology Animals Autoantibodies - biosynthesis Autoantigens - immunology Autoimmune diseases Autoimmunity Biomedical and Life Sciences Biomedicine Encephalomyelitis, Autoimmune, Experimental - etiology Encephalomyelitis, Autoimmune, Experimental - immunology Encephalomyelitis, Autoimmune, Experimental - pathology Female Freund's Adjuvant - pharmacology Histamine - physiology Hypersensitivity Immune Tolerance Immunology Infectious Diseases Insects Mice Myelin Proteolipid Protein - immunology Peptide Fragments - immunology Peptides - immunology Serotonin - physiology Thymus Gland - immunology
ISSN:	1529-2908, 1529-2916
Online Access:	Get full text
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