Sublethal irradiation promotes the metastatic potential of hepatocellular carcinoma cells

Radiotherapy (RT) represents one of the major treatment methods for cancers. However, many studies have observed that in descendant surviving tumor cells, sublethal irradiation can promote metastatic ability, which is closely related to the tumor microenvironment. We therefore investigated the funct...

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Vydáno v:	Cancer science Ročník 112; číslo 1; s. 265 - 274
Hlavní autoři:	Cao, Yulin, Yin, Yuan, Wang, Xue, Wu, Zhifeng, Liu, Yuhang, Zhang, Fuzheng, Lin, Junhua, Huang, Zhaohui, Zhou, Leyuan
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England John Wiley & Sons, Inc 01.01.2021 John Wiley and Sons Inc
Témata:	AMP Animals Antibodies Biotechnology Cancer therapies Carcinoma, Hepatocellular - pathology Celecoxib Cell adhesion & migration Cell Line, Tumor Cell Movement - radiation effects Cell, Molecular, and Stem Cell Biology cytokine Cytokines Dosimetry Genes Growth factors Hepatocellular carcinoma hepatocellular carcinoma cells Hepatocytes Hepatoma Liver - metabolism Liver - radiation effects Liver cancer Liver Neoplasms - pathology Male Matrix metalloproteinase Matrix Metalloproteinase 8 - metabolism Medical prognosis Metalloproteinase Metastases Metastasis Neoplasm Invasiveness - pathology Original Penicillin Protein kinase Radiation therapy radiotherapy Rapamycin Rats Rats, Sprague-Dawley Signal transduction Signal Transduction - radiation effects sublethal irradiation TOR protein Tumor cells Tumor microenvironment Tumors X-Rays - adverse effects cytokine radiotherapy hepatocellular carcinoma cells metastasis sublethal irradiation
ISSN:	1347-9032, 1349-7006, 1349-7006
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