Antiepileptic drugs—best practice guidelines for therapeutic drug monitoring: A position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies

Summary Although no randomized studies have demonstrated a positive impact of therapeutic drug monitoring (TDM) on clinical outcome in epilepsy, evidence from nonrandomized studies and everyday clinical experience does indicate that measuring serum concentrations of old and new generation antiepilep...

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Bibliographic Details
Published in:	Epilepsia (Copenhagen) Vol. 49; no. 7; pp. 1239 - 1276
Main Authors:	Patsalos, Philip N., Berry, David J., Bourgeois, Blaise F. D., Cloyd, James C., Glauser, Tracy A., Johannessen, Svein I., Leppik, Ilo E., Tomson, Torbjörn, Perucca, Emilio
Format:	Journal Article
Language:	English
Published:	Malden, USA Blackwell Publishing Inc 01.07.2008 Blackwell
Subjects:	Adolescent Aged Anticonvulsants - blood Anticonvulsants - pharmacokinetics Anticonvulsants - therapeutic use Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences Biological Availability Child Child, Preschool Children Cooperative Behavior Drug compliance Drug Monitoring - methods Drug Therapy, Combination Elderly Epilepsy - drug therapy Half-Life Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Infant Infant, Newborn Medical sciences Nervous system (semeiology, syndromes) Neurology Neuropharmacology Pharmacokinetics Pharmacology. Drug treatments Pregnancy Reference Values Saliva Human Nervous system diseases Epilepsy Anticonvulsant Cerebral disorder Pregnancy Drug compliance Treatment Central nervous system disease Children Pharmacokinetics Child Elderly Saliva Monitoring
ISSN:	0013-9580, 1528-1167, 1528-1167
Online Access:	Get full text
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