Three-dimensional spheroid culture of human gingiva-derived mesenchymal stem cells enhances mitigation of chemotherapy-induced oral mucositis

Mesenchymal stem cells (MSCs) are capable of regenerative and immunomodulatory functions in cell-based therapies in a variety of human diseases and injuries; however, their therapeutic efficacy and potential side effects remain major obstacles in clinical applications. We report here a 3D spheroid c...

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Veröffentlicht in:	Stem cells and development Jg. 21; H. 6; S. 937
Hauptverfasser:	Zhang, Qunzhou, Nguyen, Andrew L, Shi, Shihong, Hill, Colin, Wilder-Smith, Petra, Krasieva, Tatiana B, Le, Anh D
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 10.04.2012
Schlagworte:	Animals Cell Culture Techniques Drug-Related Side Effects and Adverse Reactions Gingiva - pathology Mesenchymal Stem Cell Transplantation Mesenchymal Stromal Cells - cytology Mice Spheroids, Cellular - pathology Stomatitis - pathology Stomatitis - prevention & control Stomatitis - therapy Treatment Outcome
ISSN:	1557-8534, 1557-8534
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