Plasma Markers of Disrupted Gut Permeability in Severe COVID-19 Patients

A disruption of the crosstalk between the gut and the lung has been implicated as a driver of severity during respiratory-related diseases. Lung injury causes systemic inflammation, which disrupts gut barrier integrity, increasing the permeability to gut microbes and their products. This exacerbates...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 12; p. 686240
Main Authors:	Giron, Leila B., Dweep, Harsh, Yin, Xiangfan, Wang, Han, Damra, Mohammad, Goldman, Aaron R., Gorman, Nicole, Palmer, Clovis S., Tang, Hsin-Yao, Shaikh, Maliha W., Forsyth, Christopher B., Balk, Robert A., Zilberstein, Netanel F., Liu, Qin, Kossenkov, Andrew, Keshavarzian, Ali, Landay, Alan, Abdel-Mohsen, Mohamed
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 09.06.2021
Subjects:	COVID-19 COVID-19 - immunology Female Gastrointestinal Microbiome - immunology Glycomics Haptoglobins - metabolism Humans Immunology inflammation Inflammation - immunology Intestines - physiology Lipidomics Male Metabolomics microbial translocation Middle Aged Permeability Protein Precursors - metabolism SARS-CoV-2 SARS-CoV-2 - physiology Tight Junctions - metabolism zonulin COVID-19 microbial translocation SARS-CoV-2 zonulin glycomics inflammation metabolomics lipidomics
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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