Computational modeling and bioinformatic analyses of functional mutations in drug target genes in Mycobacterium tuberculosis

[Display omitted] •MycoTRAP-DB, a database of mutations and their impact on normal functionality of protein in M.tb genes.•Several secondary mutations were identified with significant impact on protein structure and function.•Comprehensive information gives insight for screening of suspected hotspot...

Full description

Saved in:

Bibliographic Details
Published in:	Computational and structural biotechnology journal Vol. 19; pp. 2423 - 2446
Main Authors:	Singh, Pooja, Jamal, Salma, Ahmed, Faraz, Saqib, Najumu, Mehra, Seema, Ali, Waseem, Roy, Deodutta, Ehtesham, Nasreen Z., Hasnain, Seyed E.
Format:	Journal Article
Language:	English
Published:	Elsevier B.V 01.01.2021 Research Network of Computational and Structural Biotechnology Elsevier
Subjects:	amino acid sequences bioinformatics biotechnology diagnostic techniques drug resistance drugs genes Genome sequencing MDR mutation Mycobacterium tuberculosis MycoTRAP-DB pathogenicity prediction prioritization Secondary mutations SNPs Tuberculosis SNPs Secondary mutations MDR Tuberculosis Genome sequencing MycoTRAP-DB
ISSN:	2001-0370, 2001-0370
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!