Regulation of SIRT1 and Its Roles in Inflammation

The silent information regulator sirtuin 1 (SIRT1) protein, a highly conserved NAD + -dependent deacetylase belonging to the sirtuin family, is a post-translational regulator that plays a role in modulating inflammation. SIRT1 affects multiple biological processes by deacetylating a variety of prote...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 13; p. 831168
Main Authors:	Yang, Yunshu, Liu, Yang, Wang, Yunwei, Chao, Yongyi, Zhang, Jinxin, Jia, Yanhui, Tie, Jun, Hu, Dahai
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 11.03.2022
Subjects:	enzyme activity gene regulation Histones - metabolism Humans Immunology inflammation Inflammation - metabolism NAD - metabolism post-translational modification SIRT1 Sirtuin 1 - genetics Sirtuin 1 - metabolism Sirtuins - metabolism post-translational modification gene regulation inflammation SIRT1 enzyme activity
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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