Quantitative Water Permeability Mapping of Blood-Brain-Barrier Dysfunction in Aging

Blood-brain-barrier (BBB) dysfunction is a hallmark of aging and aging-related disorders, including cerebral small vessel disease and Alzheimer’s disease. An emerging biomarker of BBB dysfunction is BBB water exchange rate (k W ) as measured by diffusion-weighted arterial spin labeling (DW-ASL) MRI....

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Bibliographic Details

Published in:	Frontiers in aging neuroscience Vol. 14; p. 867452
Main Authors:	Ford, Jeremy N., Zhang, Qihao, Sweeney, Elizabeth M., Merkler, Alexander E., de Leon, Mony J., Gupta, Ajay, Nguyen, Thanh D., Ivanidze, Jana
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 08.04.2022
Subjects:	aging Aging Neuroscience arterial spin labeling blood-brain barrier cerebral small vessel disease glymphatic blood-brain barrier glymphatic cerebral small vessel disease aging arterial spin labeling
ISSN:	1663-4365, 1663-4365
Online Access:	Get full text
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