Effect of intrahippocampal microinjection of VU0155041, a positive allosteric modulator of mGluR4, on long term potentiation in a valproic acid-induced autistic male rat model

The precise cause of autism spectrum disorder (ASD) is not fully understood. Despite the involvement of glutamatergic dysregulation in autism, the specific contribution of mGlu4 receptors to synaptic plasticity remains unclear. Using the positive allosteric modulator VU0155041, we aimed to restore l...

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Veröffentlicht in:	IBRO neuroscience reports Jg. 16; S. 629 - 634
Hauptverfasser:	Ebrahimi, Zahra, Gholipour, Parsa, Mohammadkhani, Reihaneh, Ghahremani, Reza, Sarihi, Abdolrahman, Komaki, Alireza, Salehi, Iraj, Karimi, Seyed Asaad
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier Inc 01.06.2024 Elsevier
Schlagworte:	Autism Spectrum Disorder Long-term potentiation MGlu4 receptors Research Paper Valproic acid VU0155041 VU0155041 Autism Spectrum Disorder Valproic acid MGlu4 receptors Long-term potentiation
ISSN:	2667-2421, 2667-2421
Online-Zugang:	Volltext
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