Surveillance of transmitted HIV-1 drug resistance in Gauteng and KwaZulu-Natal Provinces, South Africa, 2005-2009

Surveillance of human immunodeficiency virus type 1 transmitted drug resistance (TDR) was conducted among pregnant women in South Africa over a 5-year period after the initiation of a large national antiretroviral treatment program. Analysis of TDR data from 9 surveys conducted between 2005 and 2009...

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Vydané v:	Clinical infectious diseases Ročník 54 Suppl 4; s. S334
Hlavní autori:	Hunt, G M, Ledwaba, J, Basson, A E, Moyes, J, Cohen, C, Singh, B, Bertagnolio, S, Jordan, M R, Puren, A, Morris, L
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 15.05.2012
Predmet:	Adolescent Adult Anti-Retroviral Agents - pharmacology Drug Resistance, Viral Female Genotyping Techniques HIV Infections - epidemiology HIV Infections - transmission HIV Infections - virology HIV-1 - classification HIV-1 - drug effects HIV-1 - genetics Humans Population Surveillance Pregnancy Pregnancy Complications, Infectious - epidemiology Pregnancy Complications, Infectious - virology Retrospective Studies South Africa - epidemiology South Africa
ISSN:	1537-6591, 1537-6591
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Abstract	Surveillance of human immunodeficiency virus type 1 transmitted drug resistance (TDR) was conducted among pregnant women in South Africa over a 5-year period after the initiation of a large national antiretroviral treatment program. Analysis of TDR data from 9 surveys conducted between 2005 and 2009 in 2 provinces of South Africa suggests that while TDR remains low (<5%) in Gauteng Province, it may be increasing in KwaZulu-Natal, with the most recent survey showing moderate (5%-15%) levels of resistance to the nonnucleoside reverse transcriptase inhibitor drug class.
AbstractList	Surveillance of human immunodeficiency virus type 1 transmitted drug resistance (TDR) was conducted among pregnant women in South Africa over a 5-year period after the initiation of a large national antiretroviral treatment program. Analysis of TDR data from 9 surveys conducted between 2005 and 2009 in 2 provinces of South Africa suggests that while TDR remains low (<5%) in Gauteng Province, it may be increasing in KwaZulu-Natal, with the most recent survey showing moderate (5%-15%) levels of resistance to the nonnucleoside reverse transcriptase inhibitor drug class.Surveillance of human immunodeficiency virus type 1 transmitted drug resistance (TDR) was conducted among pregnant women in South Africa over a 5-year period after the initiation of a large national antiretroviral treatment program. Analysis of TDR data from 9 surveys conducted between 2005 and 2009 in 2 provinces of South Africa suggests that while TDR remains low (<5%) in Gauteng Province, it may be increasing in KwaZulu-Natal, with the most recent survey showing moderate (5%-15%) levels of resistance to the nonnucleoside reverse transcriptase inhibitor drug class. Surveillance of human immunodeficiency virus type 1 transmitted drug resistance (TDR) was conducted among pregnant women in South Africa over a 5-year period after the initiation of a large national antiretroviral treatment program. Analysis of TDR data from 9 surveys conducted between 2005 and 2009 in 2 provinces of South Africa suggests that while TDR remains low (<5%) in Gauteng Province, it may be increasing in KwaZulu-Natal, with the most recent survey showing moderate (5%-15%) levels of resistance to the nonnucleoside reverse transcriptase inhibitor drug class.
Author	Ledwaba, J Singh, B Cohen, C Puren, A Basson, A E Jordan, M R Bertagnolio, S Moyes, J Hunt, G M Morris, L
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References	17067263 - AIDS Res Hum Retroviruses. 2006 Oct;22(10):945-52 20453629 - AIDS. 2010 Jul 17;24(11):1679-87 11860677 - AIDS Res Hum Retroviruses. 2002 Mar 1;18(4):295-307 19835478 - J Infect Dis. 2009 Nov 15;200(10):1503-8 20046145 - Curr Opin HIV AIDS. 2010 Jan;5(1):27-37 19578237 - Antivir Ther. 2009;14(4):523-31 18419495 - Clin Infect Dis. 2008 May 15;46(10):1589-97 21345162 - AIDS Res Hum Retroviruses. 2011 Sep;27(9):945-56 18301064 - AIDS. 2008 Feb 19;22(4):511-8 18575198 - Antivir Ther. 2008;13 Suppl 2:101-7 19801944 - J Acquir Immune Defic Syndr. 2010 Apr 1;53(4):480-4 19304876 - Bioinformatics. 2009 May 1;25(9):1197-8 21399479 - AIDS. 2011 Apr 24;25(7):905-10 16603851 - AIDS. 2006 Apr 24;20(7):995-1002 18575189 - Antivir Ther. 2008;13 Suppl 2:25-36 20395786 - AIDS. 2010 May 15;24(8):1203-12 18578063 - Antivir Ther. 2008;13 Suppl 2:1-13 19266092 - PLoS One. 2009;4(3):e4724
References_xml	– reference: 19304876 - Bioinformatics. 2009 May 1;25(9):1197-8 – reference: 18575198 - Antivir Ther. 2008;13 Suppl 2:101-7 – reference: 21345162 - AIDS Res Hum Retroviruses. 2011 Sep;27(9):945-56 – reference: 19578237 - Antivir Ther. 2009;14(4):523-31 – reference: 19835478 - J Infect Dis. 2009 Nov 15;200(10):1503-8 – reference: 21399479 - AIDS. 2011 Apr 24;25(7):905-10 – reference: 20046145 - Curr Opin HIV AIDS. 2010 Jan;5(1):27-37 – reference: 18419495 - Clin Infect Dis. 2008 May 15;46(10):1589-97 – reference: 11860677 - AIDS Res Hum Retroviruses. 2002 Mar 1;18(4):295-307 – reference: 18301064 - AIDS. 2008 Feb 19;22(4):511-8 – reference: 18578063 - Antivir Ther. 2008;13 Suppl 2:1-13 – reference: 16603851 - AIDS. 2006 Apr 24;20(7):995-1002 – reference: 17067263 - AIDS Res Hum Retroviruses. 2006 Oct;22(10):945-52 – reference: 20453629 - AIDS. 2010 Jul 17;24(11):1679-87 – reference: 18575189 - Antivir Ther. 2008;13 Suppl 2:25-36 – reference: 20395786 - AIDS. 2010 May 15;24(8):1203-12 – reference: 19801944 - J Acquir Immune Defic Syndr. 2010 Apr 1;53(4):480-4 – reference: 19266092 - PLoS One. 2009;4(3):e4724
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SubjectTerms	Adolescent Adult Anti-Retroviral Agents - pharmacology Drug Resistance, Viral Female Genotyping Techniques HIV Infections - epidemiology HIV Infections - transmission HIV Infections - virology HIV-1 - classification HIV-1 - drug effects HIV-1 - genetics Humans Population Surveillance Pregnancy Pregnancy Complications, Infectious - epidemiology Pregnancy Complications, Infectious - virology Retrospective Studies South Africa - epidemiology
Title	Surveillance of transmitted HIV-1 drug resistance in Gauteng and KwaZulu-Natal Provinces, South Africa, 2005-2009
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