Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation

Postsurgical peritoneal adhesion bands are the most important causes of intestinal obstruction, pelvic pain, and female infertility. In this study, we used a mouse model of adhesion and compared the protective effect of activated protein C (APC) to that of the Food and Drug Administration-approved a...

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Veröffentlicht in:	Blood Jg. 125; H. 8; S. 1339
Hauptverfasser:	Dinarvand, Peyman, Hassanian, Seyed Mahdi, Weiler, Hartmut, Rezaie, Alireza R
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 19.02.2015
Schlagworte:	Animals Cytokines - genetics Cytokines - metabolism Drug Evaluation, Preclinical Inflammation - drug therapy Inflammation - genetics Inflammation - metabolism Inflammation Mediators - metabolism Infusions, Parenteral Male Mice Mice, Inbred C57BL Mice, Knockout Peritoneal Diseases - genetics Peritoneal Diseases - metabolism Peritoneal Diseases - prevention & control Peritonitis - drug therapy Peritonitis - genetics Peritonitis - metabolism Postoperative Complications - genetics Postoperative Complications - metabolism Postoperative Complications - prevention & control Protein C - administration & dosage Tissue Adhesions - genetics Tissue Adhesions - metabolism Tissue Adhesions - prevention & control
ISSN:	1528-0020, 1528-0020
Online-Zugang:	Weitere Angaben
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