An immunoproteomic approach revealed antigenic proteins enhancing serodiagnosis performance of bird fancier's lung

Bird fancier's lung (BFL) caused by repeated inhalation of avian proteins is the most common form of hypersensitivity pneumonitis. However, the exact identification of proteins involved is unknown, and serological test use for diagnosis need to be standardized. The objectives of this study were...

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Bibliographic Details
Published in:	Journal of immunological methods Vol. 450; pp. 58 - 65
Main Authors:	Rouzet, Adeline, Reboux, Gabriel, Dalphin, Jean-Charles, Gondouin, Anne, De Vuyst, Paul, Balliau, Thierry, Millon, Laurence, Valot, Benoit, Roussel, Sandrine
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.11.2017 Elsevier
Subjects:	2D electrophoresis Adult Aged Aged, 80 and over Allergens - immunology Animals Area Under Curve Avian Proteins - immunology Biochemistry, Molecular Biology biomarkers Bird fancier's lung Bird Fancier's Lung - blood Bird Fancier's Lung - diagnosis Bird Fancier's Lung - immunology Birds - immunology breathing Case-Control Studies Chromatography, Liquid Ecology, environment Electrophoresis, Agar Gel Electrophoresis, Gel, Two-Dimensional ELISA Endopeptidases - immunology Enzyme Precursors - immunology Enzyme-Linked Immunosorbent Assay Escherichia coli Feces Female Genomics Health Human health and pathology Humans hypersensitivity Hypersensitivity pneumonitis immune system immunoblotting Immunoelectrophoresis Immunoglobulin Light Chains, Surrogate - immunology immunoglobulins Inhalation Exposure Life Sciences Male Middle Aged patients pigeons pneumonia Predictive Value of Tests proteomics Proteomics - methods Pulmonology and respiratory tract Recombinant antigens recombinant proteins Reproducibility of Results ROC Curve Serodiagnosis Serologic Tests Tandem Mass Spectrometry DD HVs Hypersensitivity pneumonitis Recombinant antigens HP BFL AECs 2-DE PDE LC-MS/MS Bird fancier's lung IEP IGLL1 Serodiagnosis 2D electrophoresis ProE ELISA
ISSN:	0022-1759, 1872-7905, 1872-7905
Online Access:	Get full text
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