Applications of Bacteriophages in the Treatment of Localized Infections in Humans

In the recent years, multidrug-resistant bacteria have become a global threat, and phage therapy may to be used as an alternative to antibiotics or, at least, as a supplementary approach to treatment of some bacterial infections. Here, we describe the results of bacteriophage application in clinical...

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Vydané v:Frontiers in microbiology Ročník 9; s. 1696
Hlavní autori: Morozova, Vera V., Vlassov, Valentin V., Tikunova, Nina V.
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Switzerland Frontiers Media S.A 02.08.2018
Predmet:
burns
clinical practice
diabetic foot ulcers
Microbiology
phage therapy
trophic ulcers
wounds
trophic ulcers
wounds
therapeutic bacteriophage
phage therapy
clinical practice
diabetic foot ulcers
burns
ISSN:1664-302X, 1664-302X
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Shrnutí:In the recent years, multidrug-resistant bacteria have become a global threat, and phage therapy may to be used as an alternative to antibiotics or, at least, as a supplementary approach to treatment of some bacterial infections. Here, we describe the results of bacteriophage application in clinical practice for the treatment of localized infections in wounds, burns, and trophic ulcers, including diabetic foot ulcers. This mini-review includes data from various studies available in English, as well as serial case reports published in Russian scientific literature (with, at least, abstracts accessible in English). Since, it would be impossible to describe all historical Russian publications; we focused on publications included clear data on dosage and rout of phage administration.
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Edited by: Sanna Sillankorva, University of Minho, Portugal
Reviewed by: Elizabeth Martin Kutter, The Evergreen State College, United States; Nina Chanishvili, George Eliava Institute of Bacteriophage, Microbiology and Virology, Georgia; Sarah J. Kuhl, VA Northern California Health Care System, United States
This article was submitted to Antimicrobials, Resistance and Chemotherapy, a section of the journal Frontiers in Microbiology
ISSN:1664-302X
1664-302X
DOI:10.3389/fmicb.2018.01696