Frequencies of region of difference 1 antigen-specific but not purified protein derivative-specific gamma interferon-secreting T cells correlate with the presence of tuberculosis disease but do not distinguish recent from remote latent infections

The majority of individuals infected with Mycobacterium tuberculosis achieve lifelong immune containment of the bacillus. What constitutes this effective host immune response is poorly understood. We compared the frequencies of gamma interferon (IFN-gamma)-secreting T cells specific for five region...

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Bibliographic Details
Published in:	Infection and immunity Vol. 77; no. 12; p. 5486
Main Authors:	Hinks, Timothy S C, Dosanjh, Davinder P S, Innes, John A, Pasvol, Geoffrey, Hackforth, Sarah, Varia, Hansa, Millington, Kerry A, Liu, Xiao-Qing, Bakir, Mustafa, Soysal, Ahmet, Davidson, Robert N, Gunatheesan, Rubamalar, Lalvani, Ajit
Format:	Journal Article
Language:	English
Published:	United States 01.12.2009
Subjects:	Adolescent Adult Antigens, Bacterial - immunology Bacterial Proteins - immunology Child Female Humans Immunoenzyme Techniques - methods Interferon-gamma - secretion Male Middle Aged Mycobacterium tuberculosis - immunology T-Lymphocytes - immunology Tuberculosis - diagnosis Tuberculosis - immunology Young Adult
ISSN:	1098-5522, 1098-5522
Online Access:	Get more information
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