Metabolic Constants and Plasticity of Cancer Cells in a Limiting Glucose and Glutamine Microenvironment—A Pyruvate Perspective

The metabolism of cancer cells is an issue of dealing with fluctuating and limiting levels of nutrients in a precarious microenvironment to ensure their vitality and propagation. Glucose and glutamine are central metabolites for catabolic and anabolic metabolism, which is in the limelight of numerou...

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Bibliographic Details

Published in:	Frontiers in oncology Vol. 10; p. 596197
Main Author:	Otto, Angela M.
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 08.12.2020
Subjects:	13C-glucose tracing anaplerosis glutamine glycolysis nutrient deprivation Oncology TCA-cycle pyruvate replenishment 13C-glucose tracing TCA-cycle anaplerosis nutrient deprivation glycolysis glutamine metabolic network
ISSN:	2234-943X, 2234-943X
Online Access:	Get full text
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