Anti-inflammatory effects of chlorogenic acid from Taraxacum officinale on LTA-stimulated bovine mammary epithelial cells via the TLR2/NF-κB pathway

Mastitis is an inflammatory disease caused by microbial infection. Chlorogenic acid (CGA), one of the major phenolic acids in Taraxacum officinale , has natural antioxidant and anti-inflammatory properties in various cell types; however, the effects of CGA on Lipoteichoic acid (LTA)-induced bovine m...

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Bibliographic Details
Published in:	PloS one Vol. 18; no. 3; p. e0282343
Main Authors:	Xu, Ping, Xu, Xiaobo, Fotina, Hanna, Fotina, Tetiana
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 22.03.2023 Public Library of Science (PLoS)
Subjects:	Acids Animals Anti-inflammatory agents Anti-Inflammatory Agents - pharmacology Biology and Life Sciences Cattle Chlorogenic acid Chlorogenic Acid - pharmacology Chromatography Dairy cattle Dairy industry Epithelial cells Epithelial Cells - metabolism Epithelium Female Gene expression Gram-positive bacteria High performance liquid chromatography IL-1β Infections Inflammatory diseases Interleukin 6 Interleukin-6 - genetics Interleukin-6 - pharmacology Kinases Laboratories Lipopolysaccharides - pharmacology Lipoteichoic acid Liquid chromatography Mammary gland Mammary Glands, Animal - metabolism Mastitis Medicine and Health Sciences Microorganisms Milk NF-kappa B - metabolism NF-κB protein Pathways Phenolic acids Phenols Phosphorylation Proteins Signal transduction Signaling Taraxacum Taraxacum officinale TLR2 protein Toll-Like Receptor 2 - genetics Toll-Like Receptor 2 - metabolism Toll-like receptors Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-α United States > US China Japan Ukraine
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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