Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations

Melanoma, a skin cancer associated with high mortality rates, is highly radio- and chemotherapy resistant but can also be very immunogenic. These circumstances have led to a recent surge in research into therapies aiming to boost anti-tumor immune responses in cancer patients. Among these immunother...

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Bibliographic Details

Published in:	Frontiers in oncology Vol. 8; p. 86
Main Authors:	Seidel, Judith A., Otsuka, Atsushi, Kabashima, Kenji
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 28.03.2018
Subjects:	biomarkers cancer immune checkpoint inhibitors immunotherapy melanoma Oncology side effects mode of action biomarkers immunotherapy melanoma side effects cancer immune checkpoint inhibitors
ISSN:	2234-943X, 2234-943X
Online Access:	Get full text
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