Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels

The generation of induced pluripotent stem (iPS) cells is an important tool for regenerative medicine. However, the main restriction is the risk of tumor development. In this study we found that during the early stages of somatic cell reprogramming toward a pluripotent state, specific gene expressio...

Full description

Saved in:

Bibliographic Details
Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 109; no. 34; p. 13793
Main Authors:	Margariti, Andriana, Winkler, Bernhard, Karamariti, Eirini, Zampetaki, Anna, Tsai, Tsung-neng, Baban, Dilair, Ragoussis, Jiannis, Huang, Yi, Han, Jing-Dong J, Zeng, Lingfang, Hu, Yanhua, Xu, Qingbo
Format:	Journal Article
Language:	English
Published:	United States 21.08.2012
Subjects:	Animals Antigens, CD - genetics Aorta - pathology Cadherins - genetics Cell Differentiation Cells, Cultured Cellular Reprogramming Endothelial Cells - cytology Fibroblasts - cytology Fibroblasts - metabolism Humans Induced Pluripotent Stem Cells - cytology Kruppel-Like Factor 4 Mice Mice, SCID Models, Genetic Neovascularization, Pathologic Promoter Regions, Genetic Stem Cells - cytology Stress, Mechanical Tissue Engineering - methods
ISSN:	1091-6490, 1091-6490
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!