Infrared microspectroscopy analysis of Ibuprofen release from drug eluting beads in uterine tissue

Ibuprofen loaded embolization beads (IBU-BB) have been developed to reduce inflammation and pain following uterine artery embolization for the treatment of uterine fibroids. The present work has investigated the elution properties of IBU-BB in situ after embolization with Fourier Transform Infrared...

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Bibliographic Details
Published in:	Journal of controlled release Vol. 135; no. 3; pp. 198 - 202
Main Authors:	Namur, J., Wassef, M., Pelage, J.P., Lewis, A., Manfait, M., Laurent, A.
Format:	Journal Article
Language:	English
Published:	Kidlington Elsevier B.V 05.05.2009 Elsevier
Subjects:	Animals Anti-Inflammatory Agents, Non-Steroidal - analysis Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics Biological and medical sciences Calibration Delayed-Action Preparations Dose-Response Relationship, Drug Drug eluting beads Embolization Embolization, Therapeutic Female General pharmacology Ibuprofen Ibuprofen - analysis Ibuprofen - pharmacokinetics In vivo drug release Infrared microspectroscopy Medical sciences Microspheres Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Sensitivity and Specificity Sheep, Domestic Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Time Factors Uterus - blood supply Embolization In vivo drug release Drug eluting beads Infrared microspectroscopy Ibuprofen Drug Prostaglandin-endoperoxide synthase Pharmaceutical technology Enzyme Enzyme inhibitor Non steroidal antiinflammatory agent In vivo Tissue Arylpropionic acid derivatives Oxidoreductases Release
ISSN:	0168-3659, 1873-4995, 1873-4995
Online Access:	Get full text
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