Medroxyprogesterone acetate positively modulates specific GABAA-receptor subtypes - affecting memory and cognition

Medroxyprogesterone acetate (MPA) is a progestin widely used in humans as hormone replacement therapy and at other indications. Many progestin metabolites, as the progesterone metabolite allopregnanolone, have GABAA-receptor modulatory effects and are known to affect memory, learning, appetite, and...

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Vydané v:	Psychoneuroendocrinology Ročník 141; s. 105754
Hlavní autori:	Das, Roshni, Ragagnin, Gianna, Sjöstedt, Jessica, Johansson, Maja, Haage, David, Druzin, Michael, Johansson, Staffan, Bäckström, Torbjörn
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Elsevier Ltd 01.07.2022
Predmet:	Alpha5 GABA-A receptor Dementia GABA-A receptor Medroxyprogesterone-acetate Neurosteroids Positive GABA-AR modulator Medroxyprogesterone-acetate Positive GABA-AR modulator Alpha5 GABA-A receptor Neurosteroids GABA-A receptor Dementia
ISSN:	0306-4530, 1873-3360, 1873-3360
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