Multiomics unravels the complexity of male obesity: a prospective observational study

Background Obesity is associated with varying degrees of metabolic dysfunction. In this study, we aimed to discover markers of the severity of metabolic impairment in men with obesity via a multiomics approach. Methods Thirty-two morbidly men with obesity who were candidates for Roux-en-Y gastric by...

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Veröffentlicht in:	Journal of translational medicine Jg. 23; H. 1; S. 138 - 16
Hauptverfasser:	Papadakis, Georgios E., Favre, Lucie, Zouaghi, Yassine, Vionnet, Nathalie, Niederländer, Nicolas J., Adamo, Michela, Acierno, James S., Berdous, Dassine, Boizot, Alexia, Meylan, Jenny, Ivanisevic, Julijana, Paccou, Emmanuelle, Gallart-Ayala, Hector, Reyns, Tim, Van Caeneghem, Elise, Lapauw, Bruno, Pasquier, Jérôme, Aleman, Yasser, Mantziari, Styliani, Salamin, Olivier, Nicoli, Raul, Kuuranne, Tiia, Fiers, Tom, Hagmann, Patric, Santoni, Federico, Messina, Andrea, Pitteloud, Nelly
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 30.01.2025 BioMed Central Ltd BMC
Schlagworte:	Adult Bariatric surgery Biomedical and Life Sciences Biomedicine Health aspects Humans Hypogonadism Hypogonadism - genetics Magnetic Resonance Imaging Male Male obesity Medical research Medicine, Experimental Medicine/Public Health Men Metabolic risk stratification Metabolomics Middle Aged Multiomics Nutrition & metabolism Obesity Obesity - blood Obesity - genetics Obesity - metabolism Physiological aspects Prospective Studies Testosterone - blood Transcriptome - genetics Transcriptomics Switzerland Male obesity Metabolic risk stratification Transcriptomics Hypogonadism Bariatric surgery
ISSN:	1479-5876, 1479-5876
Online-Zugang:	Volltext
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