Excretion of the Polymyxin Derivative NAB739 in Murine Urine

Extremely multiresistant strains of Enterobacteriaceae are emerging and spreading at a worrisome pace. Polymyxins are used as the last-resort therapy against such strains, in spite of their nephrotoxicity. We have previously shown that novel polymyxin derivatives NAB739 and NAB815 are less nephrotox...

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Vydané v:	Antibiotics (Basel) Ročník 9; číslo 4; s. 143
Hlavní autori:	Vaara, Martti, Vaara, Timo, Kuka, Janis, Sevostjanovs, Eduards, Grinberga, Solveiga, Dambrova, Maija, Liepinsh, Edgars
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Switzerland MDPI AG 27.03.2020 MDPI
Predmet:	Calibration Chemical properties Composition E coli Excretion extremely multiresistant strains of Enterobacteriaceae Identification and classification Kidneys Linearity Monkeys mouse pyelonephritis NAB739 Polymyxin B Polymyxins Pyelonephritis Quality control Urinary tract diseases Urinary tract infections Urine Urogenital system Finland United Kingdom > UK United States > US Germany mouse pyelonephritis NAB739 extremely multiresistant strains of Enterobacteriaceae polymyxin B
ISSN:	2079-6382, 2079-6382
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