Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions

Macrophages respond to inflammatory stimuli by modulating the expression of hundreds of genes in a defined temporal cascade, with diverse transcriptional and posttranscriptional mechanisms contributing to the regulatory network. We examined proinflammatory gene regulation in activated macrophages by...

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Bibliographic Details
Published in:	Cell Vol. 150; no. 2; p. 279
Main Authors:	Bhatt, Dev M, Pandya-Jones, Amy, Tong, Ann-Jay, Barozzi, Iros, Lissner, Michelle M, Natoli, Gioacchino, Black, Douglas L, Smale, Stephen T
Format:	Journal Article
Language:	English
Published:	United States 20.07.2012
Subjects:	Animals Chromatin - genetics Gene Expression Profiling Gene Expression Regulation Inflammation - genetics Lipid A - immunology Macrophages - immunology Macrophages - metabolism Mice Mice, Inbred C57BL Promoter Regions, Genetic Receptor, Interferon alpha-beta - genetics Receptors, Interferon - genetics RNA Splicing Sequence Analysis, RNA Transcription, Genetic
ISSN:	1097-4172, 1097-4172
Online Access:	Get more information
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