Vision 20/20: Magnetic resonance imaging-guided attenuation correction in PET/MRI: Challenges, solutions, and opportunities

Attenuation correction is an essential component of the long chain of data correction techniques required to achieve the full potential of quantitative positron emission tomography (PET) imaging. The development of combined PET/magnetic resonance imaging (MRI) systems mandated the widespread interes...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Medical physics (Lancaster) Ročník 43; číslo 3; s. 1130 - 1155
Hlavní autoři: Mehranian, Abolfazl, Arabi, Hossein, Zaidi, Habib
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States American Association of Physicists in Medicine 01.03.2016
Témata:
ANIMAL TISSUES
attenuation correction
attenuation map
Biological material, e.g. blood, urine; Haemocytometers
biomedical MRI
BIOMEDICAL RADIOGRAPHY
Brain
Clinical applications
Computed tomography
CORRECTIONS
Digital computing or data processing equipment or methods, specially adapted for specific applications
Humans
Image data processing or generation, in general
Image Processing, Computer-Assisted - methods
image registration
image segmentation
Involving electronic [emr] or nuclear [nmr] magnetic resonance, e.g. magnetic resonance imaging
KEV RANGE 100-1000
learning (artificial intelligence)
LUNGS
Machine Learning
Magnetic Resonance Imaging - methods
Measuring half‐life of a radioactive substance
Medical image artifacts
medical image processing
Medical image segmentation
Medical magnetic resonance imaging
NMR IMAGING
PET/MRI
POSITRON COMPUTED TOMOGRAPHY
positron emission tomography
Positron emission tomography (PET)
Positron-Emission Tomography - methods
PROTON DENSITY
quantification
RADIATION PROTECTION AND DOSIMETRY
RADIOLOGY AND NUCLEAR MEDICINE
Registration
RELAXATION TIME
Scintigraphy
Segmentation
SKELETON
Tissues
tracer uptake
Whole Body Imaging
tracer uptake
PET/MRI
quantification
attenuation correction
attenuation map
ISSN:0094-2405, 2473-4209
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Attenuation correction is an essential component of the long chain of data correction techniques required to achieve the full potential of quantitative positron emission tomography (PET) imaging. The development of combined PET/magnetic resonance imaging (MRI) systems mandated the widespread interest in developing novel strategies for deriving accurate attenuation maps with the aim to improve the quantitative accuracy of these emerging hybrid imaging systems. The attenuation map in PET/MRI should ideally be derived from anatomical MR images; however, MRI intensities reflect proton density and relaxation time properties of biological tissues rather than their electron density and photon attenuation properties. Therefore, in contrast to PET/computed tomography, there is a lack of standardized global mapping between the intensities of MRI signal and linear attenuation coefficients at 511 keV. Moreover, in standard MRI sequences, bones and lung tissues do not produce measurable signals owing to their low proton density and short transverse relaxation times. MR images are also inevitably subject to artifacts that degrade their quality, thus compromising their applicability for the task of attenuation correction in PET/MRI. MRI-guided attenuation correction strategies can be classified in three broad categories: (i) segmentation-based approaches, (ii) atlas-registration and machine learning methods, and (iii) emission/transmission-based approaches. This paper summarizes past and current state-of-the-art developments and latest advances in PET/MRI attenuation correction. The advantages and drawbacks of each approach for addressing the challenges of MR-based attenuation correction are comprehensively described. The opportunities brought by both MRI and PET imaging modalities for deriving accurate attenuation maps and improving PET quantification will be elaborated. Future prospects and potential clinical applications of these techniques and their integration in commercial systems will also be discussed.
Bibliografie:habib.zaidi@hcuge.ch
Telephone: +41 22 372 7258; Fax: +41 22 372 7169.
Author to whom correspondence should be addressed. Electronic mail
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0094-2405
2473-4209
DOI:10.1118/1.4941014