Clinical on-site monitoring of ß-lactam antibiotics for a personalized antibiotherapy

An appropriate antibiotherapy is crucial for the safety and recovery of patients. Depending on the clinical conditions of patients, the required dose to effectively eradicate an infection may vary. An inadequate dosing not only reduces the efficacy of the antibiotic, but also promotes the emergence...

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Bibliographic Details
Published in:	Scientific reports Vol. 7; no. 1; pp. 3127 - 10
Main Authors:	Bruch, R., Chatelle, C., Kling, A., Rebmann, B., Wirth, S., Schumann, S., Weber, W., Dincer, C., Urban, G.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 09.06.2017 Nature Publishing Group Nature Portfolio
Subjects:	101/1 101/62 142/126 631/1647/2196/2197 631/1647/277 631/61/350/877 96/95 Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - blood Anti-Bacterial Agents - pharmacokinetics Antibiotics beta-Lactams - administration & dosage beta-Lactams - blood beta-Lactams - pharmacokinetics Blood levels Cefazolin Cefazolin - administration & dosage Cefazolin - blood Cefazolin - pharmacokinetics Cefuroxime Cefuroxime - administration & dosage Cefuroxime - blood Cefuroxime - pharmacokinetics Cephalosporins Drug Monitoring - instrumentation Drug Monitoring - methods Female Humanities and Social Sciences Humans Male Microfluidic Analytical Techniques Microfluidics multidisciplinary Penicillin Penicillin-binding protein Pharmacokinetics Piperacillin Piperacillin - administration & dosage Piperacillin - blood Piperacillin - pharmacokinetics Point-of-Care Testing Precision Medicine Science Science (multidisciplinary) Surgery
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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