Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development

Hematopoietic stem cells (HSCs) first emerge in the embryonic aorta-gonad-mesonephros (AGM) region. Studies of model organisms defined intersecting signaling pathways that converge to promote HSC emergence predominantly in the ventral domain of the dorsal aorta. Much less is known about mechanisms d...

Celý popis

Podrobná bibliografia

Vydané v:	Cell stem cell Ročník 27; číslo 5; s. 822
Hlavní autori:	Crosse, Edie I, Gordon-Keylock, Sabrina, Rybtsov, Stanislav, Binagui-Casas, Anahi, Felchle, Hannah, Nnadi, Nneka C, Kirschner, Kristina, Chandra, Tamir, Tamagno, Sara, Webb, David J, Rossi, Fiona, Anderson, Richard A, Medvinsky, Alexander
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 05.11.2020
Predmet:	Endothelial Cells Gonads Hematopoiesis Hematopoietic Stem Cells Humans Mesonephros Transcriptome - genetics single cell transcriptome endothelin hematopoiesis AGM region HSC embryo spatial transcriptome
ISSN:	1875-9777, 1875-9777
On-line prístup:	Zistit podrobnosti o prístupe
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!