Triiodothyronine regulates angiogenic growth factor and cytokine secretion by isolated human decidual cells in a cell-type specific and gestational age-dependent manner

STUDY QUESTION Does triiodothyronine (T3) regulate the secretion of angiogenic growth factors and cytokines by human decidual cells isolated from early pregnancy? SUMMARY ANSWER T3 modulates the secretion of specific angiogenic growth factors and cytokines, with different regulatory patterns observe...

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Bibliographic Details
Published in:	Human reproduction (Oxford) Vol. 29; no. 6; pp. 1161 - 1172
Main Authors:	Vasilopoulou, E., Loubière, L.S., Lash, G.E., Ohizua, O., McCabe, C.J., Franklyn, J.A., Kilby, M.D., Chan, S.Y.
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01.06.2014
Subjects:	Age Factors Angiopoietin-2 - metabolism Cell Survival - drug effects Cytokines - metabolism Decidua - cytology Decidua - drug effects Decidua - metabolism Dose-Response Relationship, Drug Female Gestational Age Humans Killer Cells, Natural - cytology Killer Cells, Natural - drug effects Killer Cells, Natural - metabolism Macrophages - cytology Macrophages - drug effects Macrophages - metabolism Placenta - cytology Placenta - drug effects Placenta - metabolism Pregnancy Pregnancy Trimester, First Pregnancy Trimester, Second Receptors, Thyroid Hormone - metabolism Triiodothyronine - administration & dosage Triiodothyronine - pharmacology Vascular Endothelial Growth Factor A - metabolism angiogenic growth factors cytokines extravillous trophoblast decidua triiodothyronine
ISSN:	0268-1161, 1460-2350, 1460-2350
Online Access:	Get full text
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