Exploring the Relationship Between Schizophrenia and Cardiovascular Disease: A Genetic Correlation and Multivariable Mendelian Randomization Study

Abstract Individuals with schizophrenia have a reduced life-expectancy compared to the general population, largely due to an increased risk of cardiovascular disease (CVD). Clinical and epidemiological studies have been unable to unravel the nature of this relationship. We obtained summary-data of g...

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Bibliographic Details
Published in:	Schizophrenia bulletin Vol. 48; no. 2; pp. 463 - 473
Main Authors:	Veeneman, Rada R, Vermeulen, Jentien M, Abdellaoui, Abdel, Sanderson, Eleanor, Wootton, Robyn E, Tadros, Rafik, Bezzina, Connie R, Denys, Damiaan, Munafò, Marcus R, Verweij, Karin J H, Treur, Jorien L
Format:	Journal Article
Language:	English
Published:	US Oxford University Press 01.03.2022
Subjects:	Blood pressure Cardiovascular disease Cardiovascular Diseases - complications Cardiovascular Diseases - epidemiology Cardiovascular Diseases - psychology Correlation of Data Genetic Testing - methods Genetic Testing - statistics & numerical data Heart failure Heart rate Humans Mendelian Randomization Analysis - methods Mendelian Randomization Analysis - statistics & numerical data Regular Schizophrenia Schizophrenia - diagnosis Schizophrenia - epidemiology Schizophrenia - physiopathology coronary artery disease QT interval heart rate variability early repolarization dilated cardiomyopathy causality
ISSN:	0586-7614, 1745-1701, 1745-1701
Online Access:	Get full text
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