ShinyGO: a graphical gene-set enrichment tool for animals and plants
Abstract Motivation Gene lists are routinely produced from various omic studies. Enrichment analysis can link these gene lists with underlying molecular pathways and functional categories such as gene ontology (GO) and other databases. Results To complement existing tools, we developed ShinyGO based...
Uložené v:
| Vydané v: | Bioinformatics Ročník 36; číslo 8; s. 2628 - 2629 |
|---|---|
| Hlavní autori: | , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
England
Oxford University Press
15.04.2020
|
| Predmet: | |
| ISSN: | 1367-4803, 1367-4811, 1460-2059, 1367-4811 |
| On-line prístup: | Získať plný text |
| Tagy: |
Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
|
| Shrnutí: | Abstract
Motivation
Gene lists are routinely produced from various omic studies. Enrichment analysis can link these gene lists with underlying molecular pathways and functional categories such as gene ontology (GO) and other databases.
Results
To complement existing tools, we developed ShinyGO based on a large annotation database derived from Ensembl and STRING-db for 59 plant, 256 animal, 115 archeal and 1678 bacterial species. ShinyGO’s novel features include graphical visualization of enrichment results and gene characteristics, and application program interface access to KEGG and STRING for the retrieval of pathway diagrams and protein–protein interaction networks. ShinyGO is an intuitive, graphical web application that can help researchers gain actionable insights from gene-sets.
Availability and implementation
http://ge-lab.org/go/.
Supplementary information
Supplementary data are available at Bioinformatics online. |
|---|---|
| Bibliografia: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 1367-4803 1367-4811 1460-2059 1367-4811 |
| DOI: | 10.1093/bioinformatics/btz931 |