Neurofilament light as a predictive biomarker of unresolved chemotherapy-induced peripheral neuropathy in subjects receiving paclitaxel and carboplatin

Management of chemotherapy-induced peripheral neuropathy (CIPN) remains a significant challenge in the treatment of cancer. Risk mitigation for CIPN involves preemptive reduction of cumulative dose or reduction of dose intensity upon emergence of symptoms, despite the risk of reduced tumor efficacy....

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Bibliographic Details
Published in:	Scientific reports Vol. 12; no. 1; pp. 15593 - 9
Main Authors:	Burgess, B. L., Cho, E., Honigberg, L.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 16.09.2022 Nature Publishing Group Nature Portfolio
Subjects:	631/378 692/4028 692/53 Biomarkers Carboplatin Chemotherapy Glial fibrillary acidic protein Humanities and Social Sciences Hydrolase multidisciplinary Neurodegeneration Neuronal-glial interactions Paclitaxel Peripheral neuropathy Protein gene product 9.5 Science Science (multidisciplinary) Tau protein Tumors Ubiquitin Ubiquitin carboxy-terminal hydrolase
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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