Derivation and validation of an epigenetic frailty risk score in population-based cohorts of older adults

DNA methylation (DNAm) patterns in peripheral blood have been shown to be associated with aging related health outcomes. We perform an epigenome-wide screening to identify CpGs related to frailty, defined by a frailty index (FI), in a large population-based cohort of older adults from Germany, the E...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Nature communications Ročník 13; číslo 1; s. 5269 - 11
Hlavní autori:	Li, Xiangwei, Delerue, Thomas, Schöttker, Ben, Holleczek, Bernd, Grill, Eva, Peters, Annette, Waldenberger, Melanie, Thorand, Barbara, Brenner, Hermann
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London Nature Publishing Group UK 07.09.2022 Nature Publishing Group Nature Portfolio
Predmet:	631/208/176/1988 692/308/174 692/308/53/2423 692/700/1518 Adults Aging Algorithms Deoxyribonucleic acid DNA DNA methylation Epigenetics Frailty Humanities and Social Sciences multidisciplinary Older people Performance prediction Peripheral blood Population studies Risk analysis Risk factors Science Science (multidisciplinary) Wide screen
ISSN:	2041-1723, 2041-1723
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!