A structural analysis of M protein in coronavirus assembly and morphology

The M protein of coronavirus plays a central role in virus assembly, turning cellular membranes into workshops where virus and host factors come together to make new virus particles. We investigated how M structure and organization is related to virus shape and size using cryo-electron microscopy, t...

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Bibliographic Details
Published in:	Journal of structural biology Vol. 174; no. 1; pp. 11 - 22
Main Authors:	Neuman, Benjamin W., Kiss, Gabriella, Kunding, Andreas H., Bhella, David, Baksh, M. Fazil, Connelly, Stephen, Droese, Ben, Klaus, Joseph P., Makino, Shinji, Sawicki, Stanley G., Siddell, Stuart G., Stamou, Dimitrios G., Wilson, Ian A., Kuhn, Peter, Buchmeier, Michael J.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.04.2011
Subjects:	Cell Line Coronavirus Coronavirus - metabolism Coronavirus - ultrastructure Coronavirus M Proteins Cryo-electron microscopy Cryo-electron tomography Cryoelectron Microscopy Electron Microscope Tomography Humans Pleomorphic virus structure Viral matrix protein Viral Matrix Proteins - ultrastructure Virus Assembly - physiology Virus Assembly - radiation effects Viral matrix protein Cryo-electron tomography Coronavirus Pleomorphic virus structure Cryo-electron microscopy
ISSN:	1047-8477, 1095-8657, 1095-8657
Online Access:	Get full text
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