The Roles of NRF2 in Modulating Cellular Iron Homeostasis

Iron and oxygen are intimately linked: iron is an essential nutrient utilized as a cofactor in enzymes for oxygen transport, oxidative phosphorylation, and metabolite oxidation. However, excess labile iron facilitates the formation of oxygen-derived free radicals capable of damaging biomolecules. Th...

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Bibliographic Details

Published in:	Antioxidants & redox signaling Vol. 29; no. 17; p. 1756
Main Authors:	Kerins, Michael John, Ooi, Aikseng
Format:	Journal Article
Language:	English
Published:	United States 10.12.2018
Subjects:	iron cancer ferroptosis NRF2 heme oxygen
ISSN:	1557-7716, 1557-7716
Online Access:	Get more information
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