Immunoexpression of matrix metalloproteinase‐2 and matrix metalloproteinase‐9 in the metastasis of squamous cell carcinoma of the human tongue

Background: Squamous cell carcinoma of the tongue has frequent lymph node metastases and poor prognosis. Matrix metalloproteinase‐2 (MMP‐2) and matrix metalloproteinase‐9 (MMP‐9) are reported to degrade basement membrane, facilitating invasion and metastasis. This study determined the expression of...

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Bibliographic Details
Published in:	Australian dental journal Vol. 55; no. 4; pp. 385 - 389
Main Authors:	Zhou, CX, Gao, Y, Johnson, NW, Gao, J
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01.12.2010 Wiley-Blackwell
Subjects:	Adult Aged Aged, 80 and over Biological and medical sciences Carcinoma, Squamous Cell - enzymology Carcinoma, Squamous Cell - secondary Chi-Square Distribution Dermatology Facial bones, jaws, teeth, parodontium: diseases, semeiology Female Gene Expression Gene Expression Regulation, Neoplastic Humans Immunoenzyme Techniques Lymph Nodes - enzymology Lymphatic Metastasis - genetics Male Matrix Metalloproteinase 2 - biosynthesis Matrix Metalloproteinase 2 - genetics Matrix Metalloproteinase 9 - biosynthesis Matrix Metalloproteinase 9 - genetics Matrix metalloproteinase‐2 matrix metalloproteinase‐9 Medical sciences metastasis Middle Aged Neck Non tumoral diseases oral squamous cell carcinoma Otorhinolaryngology. Stomatology Prognosis tongue cancer Tongue Neoplasms - enzymology Tongue Neoplasms - pathology Tumors Tumors of the skin and soft tissue. Premalignant lesions Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology Young Adult Human Skin disease Squamous cell carcinoma Tongue Basal cell carcinoma Stomatology matrix metalloproteinase-9 Tongue cancer Malignant tumor Oral squamous cell carcinoma Dentistry Metastasis Matrix metalloproteinase-2 Oral cavity disease Cancer
ISSN:	0045-0421, 1834-7819, 1834-7819
Online Access:	Get full text
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