Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB

The Origin Recognition Complex (ORC) is a six-subunit protein important for the initiation of DNA replication in eukaryotic cells. Orc6 is the smallest and the least conserved among ORC subunits. It is required for the DNA replication but also has a function in cytokinesis in metazoan species, howev...

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Vydané v:	Proceedings of the National Academy of Sciences - PNAS Ročník 108; číslo 18; s. 7373
Hlavní autori:	Liu, Shixuan, Balasov, Maxim, Wang, Hongfei, Wu, Lijie, Chesnokov, Igor N, Liu, Yingfang
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 03.05.2011
Predmet:	Amino Acid Sequence Animals Bromodeoxyuridine Chromatography, Gel Cloning, Molecular Crystallization DNA Replication - genetics Drosophila Electrophoresis, Polyacrylamide Gel Green Fluorescent Proteins Humans Models, Molecular Molecular Sequence Data Origin Recognition Complex - chemistry Origin Recognition Complex - genetics Protein Binding Protein Conformation Sequence Alignment Sequence Homology Transcription Factor TFIIB - genetics Xenopus
ISSN:	1091-6490, 1091-6490
On-line prístup:	Zistit podrobnosti o prístupe
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