Glycan expression profile of signet ring cell gastric cancer cells and potential applicability of rBC2LCN-targeted lectin drug conjugate therapy

Background Signet ring cell carcinoma (SRC) is a distinct subtype of gastric cancer (GC); however, the specific characteristics of cancer cell surface glycans and glycosylation remain unclear. In this study, we investigated SRC-specific glycans using lectin microarray and evaluated the potential app...

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Veröffentlicht in:	Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association Jg. 25; H. 5; S. 896 - 905
Hauptverfasser:	Yang, Yu, Akashi, Yoshimasa, Shimomura, Osamu, Tateno, Hiroaki, Saito, Sayoko, Hiemori, Keiko, Miyazaki, Yoshihiro, Furuta, Tomoaki, Kitaguchi, Daichi, Kuroda, Yukihito, Pakavarin, Louphrasitthiphol, Oda, Tatsuya
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Singapore Springer Nature Singapore 01.09.2022 Springer Nature B.V
Schlagworte:	Abdominal Surgery Affinity Animal models Cancer Research Cell surface Exotoxin A Gastric cancer Gastroenterology Glycosylation Lectins Medicine Medicine & Public Health Oncology Original Article Polysaccharides Regression analysis Sialic acids Surgical Oncology Tumors Xenografts Lectin Signet ring cell carcinoma Gastric cancer Glycan
ISSN:	1436-3291, 1436-3305, 1436-3305
Online-Zugang:	Volltext
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