Serotonin drives striatal synaptic plasticity in a sex-related manner

Plasticity at corticostriatal synapses is a key substrate for a variety of brain functions – including motor control, learning and reward processing – and is often disrupted in disease conditions. Despite intense research pointing toward a dynamic interplay between glutamate, dopamine (DA), and sero...

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Bibliographic Details
Published in:	Neurobiology of disease Vol. 158; p. 105448
Main Authors:	Campanelli, Federica, Marino, Gioia, Barsotti, Noemi, Natale, Giuseppina, Calabrese, Valeria, Cardinale, Antonella, Ghiglieri, Veronica, Maddaloni, Giacomo, Usiello, Alessandro, Calabresi, Paolo, Pasqualetti, Massimo, Picconi, Barbara
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.10.2021 Elsevier
Subjects:	Animals Animals, Genetically Modified Dopamine Electrophysiological Phenomena Female Functional recovery Glutamic Acid - physiology Long-Term Potentiation Male Mice Neostriatum - physiology Nerve Fibers Neuronal Plasticity - physiology Parkinson Disease, Secondary - physiopathology Serotonin Serotonin - physiology Sex Characteristics Striatum Synapses - physiology Synaptic plasticity Synaptic Transmission - physiology Tph2 Tryptophan Hydroxylase - metabolism Tph2 Striatum Dopamine Functional recovery Serotonin Synaptic plasticity
ISSN:	0969-9961, 1095-953X, 1095-953X
Online Access:	Get full text
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