The PPARGC1A locus and CNS-specific PGC-1α isoforms are associated with Parkinson's Disease

Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. PGC-1α, encoded by PPARGC1A, is a transcriptional co-activator that has been implicated in the pathogenesis of neurodegenerative disorders. We recently discovered multiple new PPARGC1A transcripts that initi...

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Vydané v:	Neurobiology of disease Ročník 121; s. 34 - 46
Hlavní autori:	Soyal, Selma M., Zara, Greta, Ferger, Boris, Felder, Thomas K., Kwik, Markus, Nofziger, Charity, Dossena, Silvia, Schwienbacher, Christine, Hicks, Andrew A., Pramstaller, Peter P., Paulmichl, Markus, Weis, Serge, Patsch, Wolfgang
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Elsevier Inc 01.01.2019 Elsevier
Predmet:	haplotypes Lewy body dementia Parkinson's disease PGC-1α PPARGC1A haplotypes Parkinson's disease AD PD SNP RG Lewy body dementia SNPC PGC-1α MPTP PPARGC1A LBD
ISSN:	0969-9961, 1095-953X, 1095-953X
On-line prístup:	Získať plný text
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