Clinical utility and cost-effectiveness of bacterial 16S rRNA and targeted PCR based diagnostic testing in a UK microbiology laboratory network

16S ribosomal-ribonucleic acid polymerase chain reaction (PCR) and targeted PCR aid microbiological diagnosis in culture-negative clinical samples. Despite routine clinical use, there remains a paucity of data on their effectiveness across a variety of clinical sample types, and cost-effectiveness....

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Bibliographic Details
Published in:	Scientific reports Vol. 10; no. 1; p. 7965
Main Authors:	Aggarwal, Dinesh, Kanitkar, Tanmay, Narouz, Michael, Azadian, Berge S., Moore, Luke S. P., Mughal, Nabeela
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 14.05.2020 Nature Publishing Group
Subjects:	692/4017 692/699/255 692/700/139 Bacterial Typing Techniques Communicable Diseases - diagnosis Communicable Diseases - etiology Cost analysis Cost control Cost-Benefit Analysis Diagnosis Diagnostic tests Humanities and Social Sciences Humans Laboratories London Microbiological Techniques - economics Microbiological Techniques - methods Microbiology Molecular Diagnostic Techniques - economics Molecular Diagnostic Techniques - methods multidisciplinary Observational studies Patients Polymerase chain reaction Polymerase Chain Reaction - economics Polymerase Chain Reaction - methods Procedures and Techniques Utilization - economics Procedures and Techniques Utilization - statistics & numerical data Reproducibility of Results Retrospective Studies RNA, Ribosomal, 16S - genetics rRNA 16S Science Science (multidisciplinary) Sensitivity and Specificity United Kingdom London United Kingdom
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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