Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth

Targeting protein-protein interactions (PPIs) is a promising approach in the development of drugs for many indications. 14-3-3 proteins are a family of phosphoprotein-binding molecules with critical functions in dozens of cell signaling networks. 14-3-3s are abundant in the central nervous system, a...

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Vydané v:	Cell chemical biology Ročník 27; číslo 6; s. 657
Hlavní autori:	Kaplan, Andrew, Andrei, Sebastian A, van Regteren Altena, Anna, Simas, Tristan, Banerjee, Sara L, Kato, Nobuo, Bisson, Nicolas, Higuchi, Yusuke, Ottmann, Christian, Fournier, Alyson E
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 18.06.2020
Predmet:	14-3-3 spinal cord injury axon regeneration Rap1 polypharmacology
ISSN:	2451-9448, 2451-9448
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