Human immunodeficiency virus type 1 infection is associated with increased NK cell polyfunctionality and higher levels of KIR3DL1+ NK cells in ugandans carrying the HLA-B Bw4 motif

Natural killer (NK) cells are important innate effector cells controlled by an array of activating and inhibitory receptors. Some alleles of the inhibitory killer-cell immunoglobulin-like receptor KIR3DL1 in combination with its HLA class I ligand Bw4 have been genetically associated with slower HIV...

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Vydáno v:	Journal of virology Ročník 85; číslo 10; s. 4802
Hlavní autoři:	Eller, Michael A, Koehler, Rebecca N, Kijak, Gustavo H, Eller, Leigh Anne, Guwatudde, David, Marovich, Mary A, Michael, Nelson L, de Souza, Mark S, Wabwire-Mangen, Fred, Robb, Merlin L, Currier, Jeffrey R, Sandberg, Johan K
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.05.2011
Témata:	Adult CD56 Antigen - analysis HIV Infections - immunology HIV-1 - immunology HLA-B Antigens - analysis Humans Killer Cells, Natural - chemistry Killer Cells, Natural - immunology Lymphocyte Subsets - chemistry Lymphocyte Subsets - immunology Middle Aged Receptors, KIR3DL1 - analysis Uganda Viral Load
ISSN:	1098-5514, 1098-5514
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