The role of viscosity on skin penetration from cellulose ether‐based hydrogels

Background The rheological properties of dermal drug delivery systems are of importance when designing new formulations. Viscosity not only affects features such as spreadability and skin feel, but may also affect the skin penetration of incorporated actives. Data on the latter aspect are controvers...

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Bibliographic Details
Published in:	Skin research and technology Vol. 25; no. 5; pp. 725 - 734
Main Authors:	Binder, Lisa, Mazál, Julia, Petz, Romana, Klang, Victoria, Valenta, Claudia
Format:	Journal Article
Language:	English
Published:	England John Wiley & Sons, Inc 01.09.2019 John Wiley and Sons Inc
Subjects:	Animals Anti-Bacterial Agents - pharmacokinetics Cellulose Cellulose - pharmacokinetics Cellulose ethers confocal raman spectroscopy Drug delivery Drug delivery systems Ear, External - metabolism Ether - pharmacokinetics Formulations Gelation Gels High-performance liquid chromatography Hydrogels Hydrogels - chemistry Hydrogels - pharmacokinetics Hydrogen-Ion Concentration Liquid chromatography Original Penetration Raman spectroscopy Rheological properties Rheology - methods Skin Skin - metabolism Skin Absorption - physiology skin penetration Sodium Sulfadiazine - pharmacokinetics sulphadiazine sodium Sus scrofa Swine tape stripping Viscosity confocal raman spectroscopy sulphadiazine sodium tape stripping viscosity skin penetration rheological properties
ISSN:	0909-752X, 1600-0846, 1600-0846
Online Access:	Get full text
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